Risk-based breast cancer screening, as opposed to annual screening, has been found to be as safe as a traditional annual mammography for women ages 40 to 74. JAMA reports that a WISDOM randomized clinical trial involving more than 28,000 women shows that after about five years, the rate of advanced cancers were less in the risk-based group. Women at higher risk received more frequent imaging, while lower-risk women were screened less often. Although overall biopsies were not reduced, the report notes that breast cancer screening tends to be a “one-size-fits-all” approach, and risk-based screening offers “an opportunity to modernize screening in the precision medicine era.”
